Open AccessM-path: a compass for navigating potential metabolic pathways
Author(s) -
Michihiro Araki,
Robert Sidney Cox,
Hiroki Makiguchi,
Teppei Ogawa,
Takeshi Taniguchi,
Kohei Miyaoku,
Masahiko Nakatsui,
Kiyotaka Y. Hara,
Akihiko Kondo
Publication year - 2014
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btu750
Subject(s) - compass , path (computing) , computer science , artificial intelligence , computational biology , biology , cartography , geography , programming language
Construction of synthetic metabolic pathways promises sustainable production of diverse chemicals and materials. To design synthetic metabolic pathways of high value, computational methods are needed to expand present knowledge by mining comprehensive chemical and enzymatic information databases. Several computational methods have been already reported for the metabolic pathway design, but until now computation complexity has limited the diversity of chemical and enzymatic data used.
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