Automatic prediction of polysaccharide utilization loci in Bacteroidetes species | Zendy

Nicolas Terrapon | Zendy; Vincent Lombard | Zendy; Harry J. Gilbert | Zendy; Bernard Henrissat | Zendy

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Automatic prediction of polysaccharide utilization loci in Bacteroidetes species

Author(s) -

Nicolas Terrapon,

Vincent Lombard,

Harry J. Gilbert,

Bernard Henrissat

Publication year - 2014

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btu716

Subject(s) - bacteroidetes , biology , computational biology , genetics , genome , operon , gene , context (archaeology) , phylum , bacteroides , 16s ribosomal rna , bacteria , escherichia coli , paleontology

A bacterial polysaccharide utilization locus (PUL) is a set of physically linked genes that orchestrate the breakdown of a specific glycan. PULs are prevalent in the Bacteroidetes phylum and are key to the digestion of complex carbohydrates, notably by the human gut microbiota. A given Bacteroidetes genome can encode dozens of different PULs whose boundaries and precise gene content are difficult to predict.

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