Differential regulation enrichment analysis via the integration of transcriptional regulatory network and gene expression data | Zendy

Shining Ma | Zendy; Tao Jiang | Zendy; Rui Jiang | Zendy

Open Access

Differential regulation enrichment analysis via the integration of transcriptional regulatory network and gene expression data

Author(s) -

Shining Ma,

Tao Jiang,

Rui Jiang

Publication year - 2014

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btu672

Subject(s) - gene , computational biology , gene regulatory network , gene expression , biology , phenotype , microarray analysis techniques , regulation of gene expression , set (abstract data type) , gene expression profiling , transcriptional regulation , genetics , data mining , computer science , programming language

Although many gene set analysis methods have been proposed to explore associations between a phenotype and a group of genes sharing common biological functions or involved in the same biological process, the underlying biological mechanisms of identified gene sets are typically unexplained.

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