Novel function discovery with GeneMANIA: a new integrated resource for gene function prediction in Escherichia coli
Author(s) -
James Vlasblom,
Khalid Zuberi,
Harold Rodriguez,
Roland Arnold,
Alla Gagarinova,
Viktor Deineko,
Ashwani Kumar,
Elisa Leung,
Kamran Rizzolo,
Bahram Samanfar,
Luke J. Chang,
Sadhna Phanse,
Ashkan Golshani,
Jack Greenblatt,
Walid A. Houry,
Andrew Emili,
Quaid Morris,
Gary D. Bader,
Mohan Babu
Publication year - 2014
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btu671
Subject(s) - function (biology) , computational biology , biology , computer science , escherichia coli , biogenesis , resource (disambiguation) , protein function , gene , genetics , computer network
The model bacterium Escherichia coli is among the best studied prokaryotes, yet nearly half of its proteins are still of unknown biological function. This is despite a wealth of available large-scale physical and genetic interaction data. To address this, we extended the GeneMANIA function prediction web application developed for model eukaryotes to support E.coli.
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