Genome measures used for quality control are dependent on gene function and ancestry | Zendy

Jing Wang | Zendy; Leon Raskin | Zendy; David C. Samuels | Zendy; Yu Shyr | Zendy; Yan Guo | Zendy

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Genome measures used for quality control are dependent on gene function and ancestry

Author(s) -

Jing Wang,

Leon Raskin,

David C. Samuels,

Yu Shyr,

Yan Guo

Publication year - 2014

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btu668

Subject(s) - genome , transversion , genetics , biology , 1000 genomes project , gene , genetic genealogy , computational biology , genotype , single nucleotide polymorphism , medicine , mutation , population , environmental health

The transition/transversion (Ti/Tv) ratio and heterozygous/nonreference-homozygous (het/nonref-hom) ratio have been commonly computed in genetic studies as a quality control (QC) measurement. Additionally, these two ratios are helpful in our understanding of the patterns of DNA sequence evolution.

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