Poretools: a toolkit for analyzing nanopore sequence data | Zendy

Nicholas J. Loman | Zendy; Aaron R. Quinlan | Zendy

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Poretools: a toolkit for analyzing nanopore sequence data

Author(s) -

Nicholas J. Loman,

Aaron R. Quinlan

Publication year - 2014

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btu555

Subject(s) - minion , python (programming language) , nanopore sequencing , computer science , source code , software , nanopore , documentation , programming language , operating system , dna sequencing , engineering , dna , genetics , biology , chemical engineering

Nanopore sequencing may be the next disruptive technology in genomics, owing to its ability to detect single DNA molecules without prior amplification, lack of reliance on expensive optical components, and the ability to sequence long fragments. The MinION™ from Oxford Nanopore Technologies (ONT) is the first nanopore sequencer to be commercialized and is now available to early-access users. The MinION™ is a USB-connected, portable nanopore sequencer that permits real-time analysis of streaming event data. Currently, the research community lacks a standardized toolkit for the analysis of nanopore datasets.

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