A method for de novo nucleic acid diagnostic target discovery | Zendy

Yeting Zhang | Zendy; Yazhou Sun | Zendy

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A method for de novo nucleic acid diagnostic target discovery

Author(s) -

Yeting Zhang,

Yazhou Sun

Publication year - 2014

Publication title -

bioinformatics

Language(s) - Portuguese

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btu515

Subject(s) - computational biology , biology , source code , identification (biology) , conserved sequence , diagnostic test , computer science , genetics , base sequence , dna , botany , operating system , medicine , emergency medicine

A proper target or marker is essential in any diagnosis (e.g. an infection or cancer). An ideal diagnostic target should be both conserved in and unique to the pathogen. Currently, these targets can only be identified manually, which is time-consuming and usually error-prone. Because of the increasingly frequent occurrences of emerging epidemics and multidrug-resistant 'superbugs', a rapid diagnostic target identification process is needed.

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