Compression and fast retrieval of SNP data | Zendy

Francesco Sambo | Zendy; Barbara Di Camillo | Zendy; Gianna Toffolo | Zendy; Claudio Cobelli | Zendy

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Compression and fast retrieval of SNP data

Author(s) -

Francesco Sambo,

Barbara Di Camillo,

Gianna Toffolo,

Claudio Cobelli

Publication year - 2014

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btu495

Subject(s) - computer science , linkage disequilibrium , snp , single nucleotide polymorphism , data mining , data compression , software , epistasis , algorithm , biology , genetics , genotype , programming language , gene

The increasing interest in rare genetic variants and epistatic genetic effects on complex phenotypic traits is currently pushing genome-wide association study design towards datasets of increasing size, both in the number of studied subjects and in the number of genotyped single nucleotide polymorphisms (SNPs). This, in turn, is leading to a compelling need for new methods for compression and fast retrieval of SNP data.

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