EuGene-PP: a next-generation automated annotation pipeline for prokaryotic genomes
Author(s) -
Erika Sallet,
Jérôme Gouzy,
Thomas Schiex
Publication year - 2014
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btu366
Subject(s) - pipeline (software) , annotation , computer science , genome , computational biology , artificial intelligence , biology , genetics , programming language , gene
It is now easy and increasingly usual to produce oriented RNA-Seq data as a prokaryotic genome is being sequenced. However, this information is usually just used for expression quantification. EuGene-PP is a fully automated pipeline for structural annotation of prokaryotic genomes integrating protein similarities, statistical information and any oriented expression information (RNA-Seq or tiling arrays) through a variety of file formats to produce a qualitatively enriched annotation including coding regions but also (possibly antisense) non-coding genes and transcription start sites.
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