The cell behavior ontology: describing the intrinsic biological behaviors of real and model cells seen as active agents
Author(s) -
James P. Sluka,
Abbas Shirinifard,
Maciej Swat,
Alin Cosmanescu,
Randy Heiland,
James A. Glazier
Publication year - 2014
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btu210
Subject(s) - ontology , computer science , abstraction , representation (politics) , in silico , annotation , computational biology , artificial intelligence , biology , philosophy , biochemistry , epistemology , politics , political science , law , gene
Currently, there are no ontologies capable of describing both the spatial organization of groups of cells and the behaviors of those cells. The lack of a formalized method for describing the spatiality and intrinsic biological behaviors of cells makes it difficult to adequately describe cells, tissues and organs as spatial objects in living tissues, in vitro assays and in computational models of tissues.
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