methylC Track: visual integration of single-base resolution DNA methylation data on the WashU EpiGenome Browser | Zendy

Xin Zhou | Zendy; Daofeng Li | Zendy; Rebecca F. Lowdon | Zendy; J Costello | Zendy; Ting Wang | Zendy

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methylC Track: visual integration of single-base resolution DNA methylation data on the WashU EpiGenome Browser

Author(s) -

Xin Zhou,

Daofeng Li,

Rebecca F. Lowdon,

J Costello,

Ting Wang

Publication year - 2014

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btu191

Subject(s) - genome browser , epigenome , epigenomics , dna methylation , bisulfite sequencing , context (archaeology) , computational biology , computer science , genome , illumina methylation assay , biology , genetics , genomics , gene , paleontology , gene expression

We present methylC track, an efficient mechanism for visualizing single-base resolution DNA methylation data on a genome browser. The methylC track dynamically integrates the level of methylation, the position and context of the methylated cytosine (i.e. CG, CHG and CHH), strand and confidence level (e.g. read coverage depth in the case of whole-genome bisulfite sequencing data). Investigators can access and integrate these information visually at specific locus or at the genome-wide level on the WashU EpiGenome Browser in the context of other rich epigenomic datasets.

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