Trimmomatic: a flexible trimmer for Illumina sequence data
Author(s) -
Anthony Bolger,
Marc Lohse,
Björn Usadel
Publication year - 2014
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btu170
Subject(s) - preprocessor , computer science , flexibility (engineering) , java , data mining , data pre processing , sequence (biology) , operating system , programming language , biology , statistics , genetics , mathematics
Although many next-generation sequencing (NGS) read preprocessing tools already existed, we could not find any tool or combination of tools that met our requirements in terms of flexibility, correct handling of paired-end data and high performance. We have developed Trimmomatic as a more flexible and efficient preprocessing tool, which could correctly handle paired-end data.
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