Lacking alignments? The next-generation sequencing mapper segemehl revisited | Zendy

Christian Otto | Zendy; Peter F. Stadler | Zendy; Steve Hoffmann | Zendy

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Lacking alignments? The next-generation sequencing mapper segemehl revisited

Author(s) -

Christian Otto,

Peter F. Stadler,

Steve Hoffmann

Publication year - 2014

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btu146

Subject(s) - computer science , dna sequencing , software , computational biology , epigenomics , genome , reference genome , biology , genetics , gene , programming language , dna methylation , gene expression

Next-generation sequencing has become an important tool in molecular biology. Various protocols to investigate genomic, transcriptomic and epigenomic features across virtually all species and tissues have been devised. For most of these experiments, one of the first crucial steps of bioinformatic analysis is the mapping of reads to reference genomes.

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