Automated analysis of giant unilamellar vesicles using circular Hough transformation | Zendy

Eduard Hermann | Zendy; Stephanie Bleicken | Zendy; Yamunadevi Subburaj | Zendy; Ana J. GarcíaSáez | Zendy

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Automated analysis of giant unilamellar vesicles using circular Hough transformation

Author(s) -

Eduard Hermann,

Stephanie Bleicken,

Yamunadevi Subburaj,

Ana J. GarcíaSáez

Publication year - 2014

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btu102

Subject(s) - vesicle , software , computer science , transformation (genetics) , tracking (education) , membrane , biological system , chemistry , biology , programming language , biochemistry , gene , psychology , pedagogy

In order to obtain statistically relevant results, the study of membrane effects at the single-vesicle level requires the analysis of several hundreds of giant unilamellar vesicles (GUVs), which becomes a very time-consuming task if carried out manually. Complete and user-friendly software for fast and bias-free automated analysis has not been reported yet.

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