ChEpiMod: a knowledgebase for chemical modulators of epigenome reader domains
Author(s) -
Jamel Meslamani,
Steven M. Smith,
Roberto Sánchez,
MingMing Zhou
Publication year - 2014
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btu052
Subject(s) - epigenome , chromodomain , phd finger , bromodomain , context (archaeology) , computer science , annotation , computational biology , interactome , drug discovery , biology , bioinformatics , genetics , epigenetics , artificial intelligence , transcription factor , zinc finger , dna methylation , helicase , paleontology , rna , gene expression , gene
Epigenome reader domains are rapidly emerging as a new class of drug targets for a wide array of human diseases. To facilitate study of structure-activity relationship and small-molecule ligand design for these domains, we have created ChEpiMod. ChEpiMod is a free knowledgebase of chemical modulators with documented modulatory activity for epigenome reader domains.
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