Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays | Zendy

Martin J. Aryee | Zendy; Andrew E. Jaffe | Zendy; Héctor Corrada Bravo | Zendy; Christine LaddAcosta | Zendy; Andrew P. Feinberg | Zendy; Kasper D. Hansen | Zendy; Rafael A. Irizarry | Zendy

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Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

Author(s) -

Martin J. Aryee,

Andrew E. Jaffe,

Héctor Corrada Bravo,

Christine LaddAcosta,

Andrew P. Feinberg,

Kasper D. Hansen,

Rafael A. Irizarry

Publication year - 2014

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btu049

Subject(s) - bioconductor , dnam , computer science , suite , preprocessor , software , software suite , dna microarray , throughput , dna methylation , computational biology , data mining , biology , genetics , artificial intelligence , operating system , gene , history , gene expression , archaeology , wireless

The recently released Infinium HumanMethylation450 array (the '450k' array) provides a high-throughput assay to quantify DNA methylation (DNAm) at ∼450 000 loci across a range of genomic features. Although less comprehensive than high-throughput sequencing-based techniques, this product is more cost-effective and promises to be the most widely used DNAm high-throughput measurement technology over the next several years.

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