Computational identification of protein binding sites on RNAs using high-throughput RNA structure-probing data | Zendy

Xihao Hu | Zendy; Thomas K. F. Wong | Zendy; Zhi Lü | Zendy; TingFung Chan | Zendy; Terrence ChiKong Lau | Zendy; Siu Ming Yiu | Zendy; Kevin Y. Yip | Zendy

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Computational identification of protein binding sites on RNAs using high-throughput RNA structure-probing data

Author(s) -

Xihao Hu,

Thomas K. F. Wong,

Zhi Lü,

TingFung Chan,

Terrence ChiKong Lau,

Siu Ming Yiu,

Kevin Y. Yip

Publication year - 2013

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btt757

Subject(s) - rna , computational biology , nucleic acid structure , computer science , identification (biology) , biology , gene , genetics , botany

High-throughput sequencing has been used to probe RNA structures, by treating RNAs with reagents that preferentially cleave or mark certain nucleotides according to their local structures, followed by sequencing of the resulting fragments. The data produced contain valuable information for studying various RNA properties.

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