SigHunt: horizontal gene transfer finder optimized for eukaryotic genomes | Zendy

Kamil S. Jaroň | Zendy; Jiří C. Moravec | Zendy; Natália Martínková | Zendy

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SigHunt: horizontal gene transfer finder optimized for eukaryotic genomes

Author(s) -

Kamil S. Jaroň,

Jiří C. Moravec,

Natália Martínková

Publication year - 2013

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btt727

Subject(s) - genome , computational biology , sliding window protocol , biology , data mining , gene , computer science , genetics , window (computing) , operating system

Genomic islands (GIs) are DNA fragments incorporated into a genome through horizontal gene transfer (also called lateral gene transfer), often with functions novel for a given organism. While methods for their detection are well researched in prokaryotes, the complexity of eukaryotic genomes makes direct utilization of these methods unreliable, and so labour-intensive phylogenetic searches are used instead.

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