Mouse model phenotypes provide information about human drug targets | Zendy

Robert Hoehndorf | Zendy; Tanya Hiebert | Zendy; Nigel Hardy | Zendy; Paul N. Schofield | Zendy; Georgios V. Gkoutos | Zendy; Michel Dumontier | Zendy

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Mouse model phenotypes provide information about human drug targets

Author(s) -

Robert Hoehndorf,

Tanya Hiebert,

Nigel Hardy,

Paul N. Schofield,

Georgios V. Gkoutos,

Michel Dumontier

Publication year - 2013

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btt613

Subject(s) - drug repositioning , phenotype , computational biology , drug , identification (biology) , similarity (geometry) , drug development , drug discovery , biology , phenotypic screening , repurposing , computer science , bioinformatics , genetics , pharmacology , artificial intelligence , gene , ecology , botany , image (mathematics)

Methods for computational drug target identification use information from diverse information sources to predict or prioritize drug targets for known drugs. One set of resources that has been relatively neglected for drug repurposing is animal model phenotype.

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