Identification of important regressor groups, subgroups and individuals via regularization methods: application to gut microbiome data
Author(s) -
Tanya P. Garcia,
Samuel Müller,
Raymond J. Carroll,
Rosemary L. Walzem
Publication year - 2013
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btt608
Subject(s) - identification (biology) , microbiome , gut microbiome , regularization (linguistics) , computational biology , computer science , statistics , artificial intelligence , biology , mathematics , bioinformatics , ecology
Gut microbiota can be classified at multiple taxonomy levels. Strategies to use changes in microbiota composition to effect health improvements require knowing at which taxonomy level interventions should be aimed. Identifying these important levels is difficult, however, because most statistical methods only consider when the microbiota are classified at one taxonomy level, not multiple.
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