GPCR ontology: development and application of a G protein-coupled receptor pharmacology knowledge framework | Zendy

Magdalena J. Przydzial | Zendy; Barun Bhhatarai | Zendy; Amar Koleti | Zendy; Uma D. Vempati | Zendy; Stephan C. Schürer | Zendy

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GPCR ontology: development and application of a G protein-coupled receptor pharmacology knowledge framework

Author(s) -

Magdalena J. Przydzial,

Barun Bhhatarai,

Amar Koleti,

Uma D. Vempati,

Stephan C. Schürer

Publication year - 2013

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btt565

Subject(s) - g protein coupled receptor , ontology , pubchem , computer science , drug discovery , drugbank , data science , computational biology , bioinformatics , biology , drug , receptor , pharmacology , biochemistry , philosophy , epistemology

Novel tools need to be developed to help scientists analyze large amounts of available screening data with the goal to identify entry points for the development of novel chemical probes and drugs. As the largest class of drug targets, G protein-coupled receptors (GPCRs) remain of particular interest and are pursued by numerous academic and industrial research projects.

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