PRAP: an ab initio software package for automated genome-wide analysis of DNA repeats for prokaryotes
Author(s) -
Gwo-Liang Chen,
Yun-Juan Chang,
ChunHway Hsueh
Publication year - 2013
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btt482
Subject(s) - computational biology , genome , software , software package , dna , computer science , r package , genetics , biology , programming language , gene
Prokaryotic genome annotation has been focused mainly on identifying all genes and their protein functions. However, <30% of the prokaryotic genomes submitted to GenBank contain partial repeat features of specific types and none of the genomes contain complete repeat annotations. Deciphering all repeats in DNA sequences is an important and open task in genome annotation and bioinformatics. Hence, there is an immediate need of a tool capable of identifying full spectrum repeats in the whole genome.
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