Open AccessA wavelet-based method to exploit epigenomic language in the regulatory region
Author(s) -
Nha Nguyen,
An Vo,
KyoungJae Won
Publication year - 2013
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btt467
Subject(s) - epigenomics , epigenome , computer science , epigenetics , computational biology , biology , genetics , dna methylation , gene , gene expression
Epigenetic landscapes in the regulatory regions reflect binding condition of transcription factors and their co-factors. Identifying epigenetic condition and its variation is important in understanding condition-specific gene regulation. Computational approaches to explore complex multi-dimensional landscapes are needed.
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