Identification of active transcription factor and miRNA regulatory pathways in Alzheimer’s disease
Author(s) -
Wei Jiang,
Yan Zhang,
Fanlin Meng,
Baofeng Lian,
Xiaowen Chen,
Xuexin Yu,
Enyu Dai,
Shuyuan Wang,
Xin-Yi Liu,
Xiang Li,
Lihong Wang,
Xia Li
Publication year - 2013
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btt423
Subject(s) - microrna , biology , transcription factor , gene , computational biology , gene regulatory network , regulation of gene expression , biological pathway , gene silencing , genetics , gene expression
Alzheimer's disease (AD) is a severe neurodegenerative disease of the central nervous system that may be caused by perturbation of regulatory pathways rather than the dysfunction of a single gene. However, the pathology of AD has yet to be fully elucidated.
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