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SAPA tool: finding protein regions by combination of amino acid composition, scaled profiles, patterns and rules
Author(s) -
Josef Maier,
Alexei A. Adzhubei,
Wolfgang EggeJacobsen
Publication year - 2013
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btt411
Subject(s) - perl , javascript , computer science , source code , sequence (biology) , composition (language) , protein sequencing , sequence motif , web application , data mining , computational biology , programming language , peptide sequence , world wide web , biology , genetics , dna , linguistics , philosophy , gene
Functional modules within protein sequences are often extracted by consensus sequence patterns representing a linear motif; however, other functional regions may only be described by combined features such as amino acid composition, profiles of amino acid properties and randomly distributed short sequence motifs. If only a small number of functional examples are well characterized, the researcher needs a tool to extract similar sequences for further investigation.

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