SAPA tool: finding protein regions by combination of amino acid composition, scaled profiles, patterns and rules
Author(s) -
Josef Maier,
Alexei A. Adzhubei,
Wolfgang EggeJacobsen
Publication year - 2013
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btt411
Subject(s) - perl , javascript , computer science , source code , sequence (biology) , composition (language) , protein sequencing , sequence motif , web application , data mining , computational biology , programming language , peptide sequence , world wide web , biology , genetics , dna , linguistics , philosophy , gene
Functional modules within protein sequences are often extracted by consensus sequence patterns representing a linear motif; however, other functional regions may only be described by combined features such as amino acid composition, profiles of amino acid properties and randomly distributed short sequence motifs. If only a small number of functional examples are well characterized, the researcher needs a tool to extract similar sequences for further investigation.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom