Harnessing virtual machines to simplify next-generation DNA sequencing analysis
Author(s) -
Julie Nocq,
Magalie Celton,
Patrick Gendron,
Sébastien Lemieux,
Brian T. Wilhelm
Publication year - 2013
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btt352
Subject(s) - computer science , software , benchmarking , pace , data science , field (mathematics) , software engineering , operating system , mathematics , geodesy , marketing , pure mathematics , business , geography
The growth of next-generation sequencing (NGS) has not only dramatically accelerated the pace of research in the field of genomics, but it has also opened the door to personalized medicine and diagnostics. The resulting flood of data has led to the rapid development of large numbers of bioinformatic tools for data analysis, creating a challenging situation for researchers when choosing and configuring a variety of software for their analysis, and for other researchers trying to replicate their analysis. As NGS technology continues to expand from the research environment into clinical laboratories, the challenges associated with data analysis have the potential to slow the adoption of this technology.
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