miMsg: a target enrichment algorithm for predicted miR–mRNA interactions based on relative ranking of matched expression data
Author(s) -
Martin A. Rijlaarsdam,
David Rijlaarsdam,
Ad Gillis,
Lambert C. J. Dorssers,
Leendert H. J. Looijenga
Publication year - 2013
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btt246
Subject(s) - ranking (information retrieval) , context (archaeology) , computer science , algorithm , messenger rna , set (abstract data type) , source code , data mining , function (biology) , matlab , computational biology , bioinformatics , machine learning , biology , gene , genetics , programming language , paleontology , operating system
Algorithms predicting microRNA (miR)-mRNA interactions generate high numbers of possible interactions, many of which might be non-existent or irrelevant in a certain biological context. It is desirable to develop a transparent, user-friendly, unbiased tool to enrich miR-mRNA predictions.
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