Open AccessSystematic tracking of dysregulated modules identifies novel genes in cancer
Author(s) -
Sriganesh Srihari,
Mark A. Ragan
Publication year - 2013
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btt191
Subject(s) - tracking (education) , computational biology , gene , computer science , biology , genetics , psychology , pedagogy
Deciphering the modus operandi of dysregulated cellular mechanisms in cancer is critical to implicate novel cancer genes and develop effective anti-cancer therapies. Fundamental to this is meticulous tracking of the behavior of core modules, including complexes and pathways across specific conditions in cancer.
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