Janus—a comprehensive tool investigating the two faces of transcription | Zendy

Matthias Barann | Zendy; Daniela Esser | Zendy; Ulrich C. Klostermeier | Zendy; Tuuli Lappalainen | Zendy; Anne Luzius | Zendy; J. W. Kuiper | Zendy; Ole Ammerpohl | Zendy; Inga Vater | Zendy; Reiner Siebert | Zendy; Vyacheslav Amstislavskiy | Zendy; Ralf Sudbrak | Zendy; Hans Lehrach | Zendy; Stefan Schreiber | Zendy; Philip Rosenstiel | Zendy

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Janus—a comprehensive tool investigating the two faces of transcription

Author(s) -

Matthias Barann,

Daniela Esser,

Ulrich C. Klostermeier,

Tuuli Lappalainen,

Anne Luzius,

J. W. Kuiper,

Ole Ammerpohl,

Inga Vater,

Reiner Siebert,

Vyacheslav Amstislavskiy,

Ralf Sudbrak,

Hans Lehrach,

Stefan Schreiber,

Philip Rosenstiel

Publication year - 2013

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btt185

Subject(s) - janus , computer science , computational biology , transcription (linguistics) , biology , genetics , programming language , philosophy , linguistics

Protocols to generate strand-specific transcriptomes with next-generation sequencing platforms have been used by the scientific community roughly since 2008. Strand-specific reads allow for detection of antisense events and a higher resolution of expression profiles enabling extension of current transcript annotations. However, applications making use of this strandedness information are still scarce.

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