Open AccessExome-based analysis for RNA epigenome sequencing data
Author(s) -
Jia Meng,
Xiaodong Cui,
Manjeet K. Rao,
Yidong Chen,
Yufei Huang
Publication year - 2013
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btt171
Subject(s) - epigenome , computational biology , rna , computer science , exome , rna seq , transcriptome , pipeline (software) , biology , exome sequencing , genetics , gene , mutation , dna methylation , gene expression , programming language
Fragmented RNA immunoprecipitation combined with RNA sequencing enabled the unbiased study of RNA epigenome at a near single-base resolution; however, unique features of this new type of data call for novel computational techniques.
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