APP2: automatic tracing of 3D neuron morphology based on hierarchical pruning of a gray-weighted image distance-tree
Author(s) -
Hang Xiao,
Hanchuan Peng
Publication year - 2013
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btt170
Subject(s) - tracing , computer science , pruning , artificial intelligence , software , fast marching method , computer vision , grayscale , voxel , robustness (evolution) , pattern recognition (psychology) , image (mathematics) , biochemistry , chemistry , gene , agronomy , biology , programming language , operating system
Tracing of neuron morphology is an essential technique in computational neuroscience. However, despite a number of existing methods, few open-source techniques are completely or sufficiently automated and at the same time are able to generate robust results for real 3D microscopy images.
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