Fast simulation of reconstructed phylogenies under global time-dependent birth–death processes | Zendy

Sebastian Höhna | Zendy

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Fast simulation of reconstructed phylogenies under global time-dependent birth–death processes

Author(s) -

Sebastian Höhna

Publication year - 2013

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btt153

Subject(s) - phylogenetic tree , diversification (marketing strategy) , computer science , independent and identically distributed random variables , birth–death process , usability , genetic algorithm , replicate , phylogenetic comparative methods , phylogenetics , process (computing) , biology , evolutionary biology , statistics , mathematics , random variable , demography , population , biochemistry , marketing , human–computer interaction , sociology , gene , business , operating system

Diversification rates and patterns may be inferred from reconstructed phylogenies. Both the time-dependent and the diversity-dependent birth-death process can produce the same observed patterns of diversity over time. To develop and test new models describing the macro-evolutionary process of diversification, generic and fast algorithms to simulate under these models are necessary. Simulations are not only important for testing and developing models but play an influential role in the assessment of model fit.

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