MCScanX-transposed: detecting transposed gene duplications based on multiple colinearity scans | Zendy

Yupeng Wang | Zendy; Jingping Li | Zendy; Andrew H. Paterson | Zendy

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MCScanX-transposed: detecting transposed gene duplications based on multiple colinearity scans

Author(s) -

Yupeng Wang,

Jingping Li,

Andrew H. Paterson

Publication year - 2013

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btt150

Subject(s) - gene duplication , biology , computational biology , gene , computer science , genetics

Gene duplication occurs via different modes such as segmental and single-gene duplications. Transposed gene duplication, a specific form of single-gene duplication, 'copies' a gene from an ancestral chromosomal location to a novel location. MCScanX is a toolkit for detection and evolutionary analysis of gene colinearity. We have developed MCScanX-transposed, a software package to detect transposed gene duplications that occurred within different epochs, based on execution of MCScanX within and between related genomes. MCScanX-transposed can be also used for integrative analysis of gene duplication modes for a genome and to annotate a gene family of interest with gene duplication modes.

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