BRANCH: boosting RNA-Seq assemblies with partial or related genomic sequences
Author(s) -
Ergude Bao,
Tao Jiang,
Thomas Girke
Publication year - 2013
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btt127
Subject(s) - contig , de novo transcriptome assembly , computational biology , sequence assembly , biology , genome , transcriptome , rna seq , genomics , genetics , computer science , gene , gene expression
De novo transcriptome assemblies of RNA-Seq data are important for genomics applications of unsequenced organisms. Owing to the complexity and often incomplete representation of transcripts in sequencing libraries, the assembly of high-quality transcriptomes can be challenging. However, with the rapidly growing number of sequenced genomes, it is now feasible to improve RNA-Seq assemblies by guiding them with genomic sequences.
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