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BION web server: predicting non-specifically bound surface ions
Author(s) -
Marharyta Petukh,
Taylor Kimmet,
Emil Alexov
Publication year - 2013
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btt032
Subject(s) - computer science , download , web server , bounded function , ion , upper and lower bounds , surface (topology) , web application , world wide web , chemistry , the internet , mathematics , geometry , mathematical analysis , organic chemistry
Ions are essential component of the cell and frequently are found bound to various macromolecules, in particular to proteins. A binding of an ion to a protein greatly affects protein's biophysical characteristics and needs to be taken into account in any modeling approach. However, ion's bounded positions cannot be easily revealed experimentally, especially if they are loosely bound to macromolecular surface.

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