Systematic inference of highways of horizontal gene transfer in prokaryotes | Zendy

Mukul S. Bansal | Zendy; Guy Banay | Zendy; Timothy J. Harlow | Zendy; J. Peter Gogarten | Zendy; Ron Shamir | Zendy

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Systematic inference of highways of horizontal gene transfer in prokaryotes

Author(s) -

Mukul S. Bansal,

Guy Banay,

Timothy J. Harlow,

J. Peter Gogarten,

Ron Shamir

Publication year - 2013

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btt021

Subject(s) - horizontal gene transfer , inference , computational biology , gene , biology , computer science , genetics , genome , artificial intelligence

Horizontal gene transfer (HGT) plays a crucial role in the evolution of prokaryotic species. Typically, no more than a few genes are horizontally transferred between any two species. However, several studies identified pairs of species (or linages) between which many different genes were horizontally transferred. Such a pair is said to be linked by a highway of gene sharing. Inferring such highways is crucial to understanding the evolution of prokaryotes and for inferring past symbiotic and ecological associations among different species.

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