Musket: a multistage k-mer spectrum-based error corrector for Illumina sequence data
Author(s) -
Yongchao Liu,
Jan Schröder,
Bertil Schmidt
Publication year - 2012
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bts690
Subject(s) - sequence (biology) , computer science , k mer , algorithm , spectrum (functional analysis) , illumina dye sequencing , dna sequencing , biology , genetics , physics , dna , quantum mechanics
The imperfect sequence data produced by next-generation sequencing technologies have motivated the development of a number of short-read error correctors in recent years. The majority of methods focus on the correction of substitution errors, which are the dominant error source in data produced by Illumina sequencing technology. Existing tools either score high in terms of recall or precision but not consistently high in terms of both measures.
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