Open AccessLengthening of 3′UTR increases with morphological complexity in animal evolution
Author(s) -
Cho-Yi Chen,
ShuiTein Chen,
HsuehFen Juan,
HsuanCheng Huang
Publication year - 2012
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bts623
Subject(s) - untranslated region , biology , gene , microrna , computational biology , three prime untranslated region , messenger rna , regulation of gene expression , genetics , evolutionary biology
Evolutionary expansion of gene regulatory circuits seems to boost morphological complexity. However, the expansion patterns and the quantification relationships have not yet been identified. In this study, we focus on the regulatory circuits at the post-transcriptional level, investigating whether and how this principle may apply.
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