SortMeRNA: fast and accurate filtering of ribosomal RNAs in metatranscriptomic data
Author(s) -
Evguenia Kopylova,
Laurent Noé,
Hélène Touzet
Publication year - 2012
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bts611
Subject(s) - ribosomal rna , computational biology , biology , rna , coding (social sciences) , computer science , gene , genetics , statistics , mathematics
The application of next-generation sequencing (NGS) technologies to RNAs directly extracted from a community of organisms yields a mixture of fragments characterizing both coding and non-coding types of RNAs. The task to distinguish among these and to further categorize the families of messenger RNAs and ribosomal RNAs (rRNAs) is an important step for examining gene expression patterns of an interactive environment and the phylogenetic classification of the constituting species.
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