Advanced Complex Trait Analysis | Zendy

Alan Gray | Zendy; Isobel D. Stewart | Zendy; Albert Tenesa | Zendy

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Advanced Complex Trait Analysis

Author(s) -

Alan Gray,

Isobel D. Stewart,

Albert Tenesa

Publication year - 2012

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bts571

Subject(s) - computer science , software , mit license , source code , linear algebra , code (set theory) , node (physics) , parallel computing , programming language , mathematics , set (abstract data type) , geometry , structural engineering , engineering

The Genome-wide Complex Trait Analysis (GCTA) software package can quantify the contribution of genetic variation to phenotypic variation for complex traits. However, as those datasets of interest continue to increase in size, GCTA becomes increasingly computationally prohibitive. We present an adapted version, Advanced Complex Trait Analysis (ACTA), demonstrating dramatically improved performance.

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