Antisense transcription is coupled to nucleosome occupancy in sense promoters | Zendy

Zhiming Dai | Zendy; Xianhua Dai | Zendy

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Antisense transcription is coupled to nucleosome occupancy in sense promoters

Author(s) -

Zhiming Dai,

Xianhua Dai

Publication year - 2012

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bts534

Subject(s) - sense (electronics) , promoter , transcription (linguistics) , nucleosome , biology , rna polymerase ii , general transcription factor , genetics , computational biology , chromatin , dna , gene expression , gene , chemistry , linguistics , philosophy

Genome-wide pervasive transcription is widespread in eukaryotes, revealing an extensive array of antisense transcription that involves hundreds of previously unknown non-coding RNAs. Individual cases have shown that antisense transcription influences sense transcription, however, genome-wide mechanisms of how antisense transcription regulates sense transcription remain to be elucidated.

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