RazerS 3: Faster, fully sensitive read mapping | Zendy

David Weese | Zendy; Manuel Holtgrewe | Zendy; Knut Reinert | Zendy

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RazerS 3: Faster, fully sensitive read mapping

Author(s) -

David Weese,

Manuel Holtgrewe,

Knut Reinert

Publication year - 2012

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bts505

Subject(s) - computer science , sensitivity (control systems) , mit license , os x , code (set theory) , key (lock) , software , parallel computing , implementation , source code , throughput , license , margin (machine learning) , operating system , programming language , set (abstract data type) , electronic engineering , machine learning , engineering , wireless

During the past years, next-generation sequencing has become a key technology for many applications in the biomedical sciences. Throughput continues to increase and new protocols provide longer reads than currently available. In almost all applications, read mapping is a first step. Hence, it is crucial to have algorithms and implementations that perform fast, with high sensitivity, and are able to deal with long reads and a large absolute number of insertions and deletions.

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