Fast and accurate read alignment for resequencing | Zendy

John C. Mu | Zendy; Hui Jiang | Zendy; Amirhossein Kiani | Zendy; Marghoob Mohiyuddin | Zendy; Narges Bani Asadi | Zendy; Wing Hung Wong | Zendy

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Fast and accurate read alignment for resequencing

Author(s) -

John C. Mu,

Hui Jiang,

Amirhossein Kiani,

Marghoob Mohiyuddin,

Narges Bani Asadi,

Wing Hung Wong

Publication year - 2012

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bts450

Subject(s) - computer science , indel , workflow , task (project management) , reference genome , alignment free sequence analysis , key (lock) , sequence (biology) , sequence alignment , multiple sequence alignment , dna sequencing , data mining , operating system , genetics , biology , database , gene , management , peptide sequence , genotype , single nucleotide polymorphism , economics

Next-generation sequence analysis has become an important task both in laboratory and clinical settings. A key stage in the majority sequence analysis workflows, such as resequencing, is the alignment of genomic reads to a reference genome. The accurate alignment of reads with large indels is a computationally challenging task for researchers.

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