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TLM-Tracker: software for cell segmentation, tracking and lineage analysis in time-lapse microscopy movies
Author(s) -
Johannes Klein,
Stefan Leupold,
Ilona Biegler,
Rebekka Biedendieck,
Richard Münch,
Dieter Jahn
Publication year - 2012
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bts424
Subject(s) - executable , graphical user interface , software , computer science , segmentation , context (archaeology) , matlab , interface (matter) , tracking (education) , image segmentation , computer vision , artificial intelligence , programming language , biology , operating system , psychology , paleontology , pedagogy , bubble , maximum bubble pressure method
Time-lapse imaging in combination with fluorescence microscopy techniques enable the investigation of gene regulatory circuits and uncovered phenomena like culture heterogeneity. In this context, computational image processing for the analysis of single cell behaviour plays an increasing role in systems biology and mathematical modelling approaches. Consequently, we developed a software package with graphical user interface for the analysis of single bacterial cell behaviour.

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