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Evolution of gene neighborhoods within reconciled phylogenies
Author(s) -
Sèverine Bérard,
Coralie Gallien,
Bastien Boussau,
Gergely J. Szöllősi,
Vincent Daubin,
Éric Tannier
Publication year - 2012
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bts374
Subject(s) - genome , adjacency list , phylogenetic tree , gene duplication , biology , gene , tree (set theory) , phylogenetics , evolutionary biology , adjacency matrix , phylogenetic network , computational biology , set (abstract data type) , genetics , computer science , graph , combinatorics , algorithm , mathematics , theoretical computer science , programming language
Most models of genome evolution integrating gene duplications, losses and chromosomal rearrangements are computationally intract able, even when comparing only two genomes. This prevents large-scale studies that consider different types of genome structural variations.

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