JETTA: junction and exon toolkits for transcriptome analysis
Author(s) -
Junhee Seok,
Weihong Xu,
Hong Gao,
Ronald W. Davis,
Wenzhong Xiao
Publication year - 2012
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bts134
Subject(s) - exon , software , computational biology , rna splicing , visualization , computer science , alternative splicing , genome , identification (biology) , transcriptome , biology , data mining , bioinformatics , genetics , gene , gene expression , operating system , rna , botany
High-throughput genome-wide studies of alternatively spliced mRNA transcripts have become increasingly important in clinical research. Consequently, easy-to-use software tools are required to process data from these studies, for example, using exon and junction arrays. Here, we introduce JETTA, an integrated software package for the calculation of gene expression indices as well as the identification and visualization of alternative splicing events. We demonstrate the software using data of human liver and muscle samples hybridized on an exon-junction array.
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