Open AccessA co-module approach for elucidating drug–disease associations and revealing their molecular basis
Author(s) -
Shiwen Zhao,
Shao Li
Publication year - 2012
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bts057
Subject(s) - drug , closeness , disease , computational biology , bayesian network , drug repositioning , drug discovery , gene , computer science , bioinformatics , medicine , biology , pharmacology , genetics , machine learning , mathematics , mathematical analysis
Understanding how drugs and diseases are associated in the molecular level is of critical importance to unveil disease mechanisms and treatments. Until recently, few studies attempt end to discover important gene modules shared by both drugs and diseases.
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