SynaptomeDB: an ontology-based knowledgebase for synaptic genes | Zendy

Mehdi Pirooznia | Zendy; Tao Wang | Zendy; Dimitrios Avramopoulos | Zendy; David Valle | Zendy; Gareth Thomas | Zendy; Richard L. Huganir | Zendy; Fernando S. Goes | Zendy; James B. Potash | Zendy; Peter P. Zandi | Zendy

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SynaptomeDB: an ontology-based knowledgebase for synaptic genes

Author(s) -

Mehdi Pirooznia,

Tao Wang,

Dimitrios Avramopoulos,

David Valle,

Gareth Thomas,

Richard L. Huganir,

Fernando S. Goes,

James B. Potash,

Peter P. Zandi

Publication year - 2012

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bts040

Subject(s) - synapse , gene , encode , computational biology , function (biology) , biology , neuroscience , genetics

The synapse is integral to the function of the brain and may be an important source of dysfunction underlying many neuropsychiatric disorders. Consequently, it is an excellent candidate for large-scale genomic and proteomic study. However, while the tools and databases available for the annotation of high-throughput DNA and protein are generally robust, a comprehensive resource dedicated to the integration of information about the synapse is lacking.

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