Mining and evaluation of molecular relationships in literature
Author(s) -
Christian Senger,
Björn Grüning,
Anika Erxleben,
Kersten Döring,
Hitesh Patel,
Stephan Flemming,
Irmgard Merfort,
Stefan Günther
Publication year - 2012
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/bts026
Subject(s) - pubchem , uniprot , computer science , information retrieval , cheminformatics , similarity (geometry) , computational biology , protein sequencing , protein superfamily , bioinformatics , world wide web , data mining , biology , gene , peptide sequence , genetics , artificial intelligence , image (mathematics)
Specific information on newly discovered proteins is often difficult to find in literature. Particularly if only sequences and no common names of proteins or genes are available, preceding sequence similarity searches can be crucial for the process of information collection. In drug research, it is important to know whether a small molecule targets only one specific protein or whether similar or homologous proteins are also influenced that may account for possible side effects.
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