StochSens—matlab package for sensitivity analysis of stochastic chemical systems | Zendy

Michał Komorowski | Zendy; Justina Žurauskienė | Zendy; Michael P. H. Stumpf | Zendy

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StochSens—matlab package for sensitivity analysis of stochastic chemical systems

Author(s) -

Michał Komorowski,

Justina Žurauskienė,

Michael P. H. Stumpf

Publication year - 2012

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btr714

Subject(s) - sensitivity (control systems) , matlab , computer science , software package , biological system , biochemical engineering , software , computational science , chemistry , programming language , engineering , electronic engineering , biology

The growing interest in the role of stochasticity in biochemical systems drives the demand for tools to analyse stochastic dynamical models of chemical reactions. One powerful tool to elucidate performance of dynamical systems is sensitivity analysis. Traditionally, however, the concept of sensitivity has mainly been applied to deterministic systems, and the difficulty to generalize these concepts for stochastic systems results from necessity of extensive Monte Carlo simulations.

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